Ketamine Infusion

Discover how a ketamine infusion can relieve various types of depression, suicidal thinking, post-traumatic stress disorder (PTSD), anxiety, obsessive-compulsive disorder (OCD), and other mood disorders.

What is ketamine?

Ketamine is an anesthetic that was approved by the FDA in 1970 and quickly became one of the most widely used anesthetics in the world. It has the ability to anesthetize patients quickly and safely with few side effects. Unlike many other anesthetics, ketamine does not depress patients’ breathing or circulatory systems, so it is commonly used on the battlefield and in environments without adequate monitoring equipment. 

What is treatment like at a ketamine infusion clinic?

While every ketamine infusion clinic operates differently, treatment will generally begin with a consultation where you discuss your condition(s) and treatment history, complete assessments of the severity of your symptoms, review your treatment plan, undergo a brief physical exam, and discuss any other questions or concerns that weren’t answered in prior consultations with the clinic. At Ketamine Clinics LA, each individual session includes a ketamine infusion through an IV while you recline in a safe, quiet, relaxing environment with pillows, blankets, noise-cancelling headphones, calming music, and continuous monitoring of your vital signs and demeanor by a highly-trained and compassionate medical team.

Is Ketamine Right For Me?


What ketamine benefits are there?

Ketamine benefits vary depending upon your condition type and severity. In most cases, you’ll see a substantial improvement in your symptoms, usually 50% or greater, and sometimes even total relief. Most patients see improved mood and function after treatment and are better able to be social, excel at work, be physically active, get healthier nutrition, and improved quality of sleep.

For more than 20 years, ketamine-based treatments have become an increasingly popular solution for difficult to treat conditions, including treatment-resistant depression, suicidal thinking, post-traumatic stress disorder (PTSD), anxiety, obsessive-compulsive disorder (OCD), other mood disorders,  Reflex Sympathetic Dystrophy (RSD), and other neuropathic conditions. Scientifically proven to work quickly and safely with substantial relief in over 50 clinical research studies at prestigious institutions, ketamine therapy has been called the biggest breakthrough treatment of its kind in 50 years.

What is the ketamine infusion therapy success rate?

The intravenous ketamine infusion therapy success rate is the highest because of the specific mechanism of action (how the body receives, processes, and is affected by the medicine) and the 100% bioavailability (how much medicine enters the bloodstream and can have an effect) that is only possible with the IV route of administration. This ketamine success rate has been proven to be much higher than ketamine administered by other methods as well as much higher than traditional prescription treatments, in some cases almost two and a half times higher. While there is some indication of other routes of administration (ways of getting the medicine) helping treat mood disorders, none of them have been proven as safe, effective, and fast-acting as the intravenous route.

At Ketamine Clinics Los Angeles, we focus exclusively on administering ketamine intravenously for the reasons listed above. KCLA is an evidence-based practice that is motivated by science, continuity of care, and maximum therapeutic benefit for our patients. We have an 83% success rate in treating mood disorders through IV infusions of ketamine at our clinic, and the patient experience is significantly more comfortable and relaxing than alternative routes of administration (ROAs.)

Ketamine infusion treatment

What do the studies say about ketamine infusion therapy?

More than 50 peer-reviewed clinical trials at leading medical institutions and universities have proven the efficacy of ketamine infusion therapy for depression, and other mood disorders. There are at least an additional 70 studies about ketamine’s tremendous impact on treating mood disorders underway. Most of these studies have singled out severe, treatment-resistant cases that have not responded to most of the conventional treatment options and they still report a success rate of around 70% or higher among patients. Based on the data and our experience of providing infusions full time since January of 2014, patients with less resistant conditions will benefit even more often, which is part of why we have an 83% success rate at Ketamine Clinics of LA.

What does the World Health Organization say about ketamine?

Ketamine is one of only two anesthetics listed by the World Health Organization (WHO) as an “essential medicine.” The WHO is a specialized agency of the United Nations concerned with international public health. Their essential medicines are “those medicines that satisfy the health care needs of the majority of the population; they should, therefore, be available at all times in adequate amounts and in appropriate dosage forms, at a price the community can afford.” WHO’s essential medicines are the basis for many countries’ national drug policies.

Can ketamine-based treatments be used to treat suicidal thoughts?

Ketamine shows tremendous promise for suicide prevention. Yale, Stanford, NYU, USC, UCLA, Cleveland Clinic, The National Institute of Mental Health, Massachusetts General Hospital, and Mt. Sinai are just a few of the leading institutions that have conducted research proving ketamine’s efficacy for the treatment of suicidality.

Is it better for a ketamine clinic to give multiple infusions or a single infusion?

Much of the early research on ketamine for depression and other mood disorders was based on a single infusion but that poses two main problems. First, many patients don’t respond to treatment until after their second or third infusion, while some require a full series of six before experiencing significant relief from their symptoms. This led to some patients being deemed “non-responders” when they might have responded well if they had additional treatment. The second problem is the relief for the “responders” was generally reported to last an average of 7-10 days with a single infusion, not accounting for the additional duration that multiple infusions can provide. This caused many early critics to say, “It works, but it doesn’t last.”

These findings inspired the care team at Ketamine Clinics of Los Angeles to pioneer a series of six infusions over 2-3 weeks, each 55 minutes long, producing more pronounced and much longer-lasting benefits. As the premiere ketamine clinic, many research papers were published on the enhanced benefits of the multiple infusion protocol after our use of this method. See our press and research page for details.

Contact us today to move forward with your path towards a life free of the symptoms that are holding you back. We offer free phone consultations with our care team to ensure you get all the information you need in order to make the right decision about your health.


Lauren – Mother of PTSD and depression patient

I saw my son once again.

Although all the medical treatment Matt has received was valuable in some way, the only time in 16 years I saw the person who is my son once again quietly emerge, was after the ketamine infusions.

Allen – Engineer

My successes have been phenomenal.

I have cut down on my Effexor to 75 Mg per day. I have eliminated lithium from my regiment and haven’t needed ambien for about month now to sleep. My klonopin I’ve reduced to once every other day. The infusions really helped my depression and chronic pain in my neck. My depression has never been better and I am cutting down on my other medications with great success. Thank you, thank you Dr. Mandel!

Katharine – Registered Nurse

When I found Ketamine Clinics of Los Angeles,

When I found Ketamine Clinics of Los Angeles and began to research the treatment, I felt my spirits lift. I felt hope. From the moment I called their office, I knew I was in good hands. As someone who works in healthcare, I couldn’t believe how kind and attentive Dr. Mandel and his entire staff were. I know they really care about me. The treatment is the only thing in more than 30 years that has produced such rapid and dramatic improvement in my mood.

Keith – Lawyer

My doctor recommended that I try ketamine

My doctor recommended that I try ketamine at this time because he considers that there is now enough clinical information to make an informed decision about its effectiveness and side effects, and specifically recommended Dr. Mandel, who even with a glowing recommendation from someone for whom I have tremendous respect, vastly exceeded all of my expectations.

Alex – Teacher

Dr. Mandel has truly made my unlivable life, livable again.

Dr. Mandel has truly made my unlivable life, livable again. My ability to get out of bed early and or nearly right as I wake up has significantly improved. I’m able to keep up with my incredibly hectic schedule. My overall mood is high and lethargy is low. My social anxiety is at an all time low, and I haven’t had a panic attack since my first infusion.

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